In case you haven’t seen our recent paper, you can download the paper here (subscription required): http://dx.doi.org/10.1038/nbt.2198
Performance comparison of benchtop high-throughput sequencing platforms
Nature Biotechnology advance online publication published online 22 April 2012
Nicholas J Loman, Raju V Misra, Timothy J Dallman, Chrystala Constantinidou, Saheer E Gharbia, John Wain & Mark J Pallen
Here is a press release on the blog of our newly launched Institute of Microbiology and Infection: http://imicrobham.blogspot.co.uk/2012/04/performance-comparison-of-benchtop-high.html
And here are some links to the lively coverage in the blogosphere:
http://www.nature.com/news/next-generation-genome-sequencers-compared-1.10497
http://flxlexblog.wordpress.com/2012/04/22/fast-genome-sequencing-of-pathogenic-bacteria-which-benchtop-instrument-to-choose/
http://core-genomics.blogspot.co.uk/2012/04/battle-of-benchtopsmiseq-vs-ion-vs-454.html
http://imicrobham.blogspot.co.uk/2012/04/performance-comparison-of-benchtop-high.html
http://flxlexblog.wordpress.com/2012/04/22/fast-genome-sequencing-of-pathogenic-bacteria-which-benchtop-instrument-to-choose/
http://core-genomics.blogspot.co.uk/2012/04/battle-of-benchtopsmiseq-vs-ion-vs-454.html
http://imicrobham.blogspot.co.uk/2012/04/performance-comparison-of-benchtop-high.html
http://flxlexblog.wordpress.com/2012/05/09/loman-et-al-reflects-the-past-not-the-present-a-rebuttal/
The paper is currently the most downloaded on the Nature Biotechnology web site!
[...] Ion Torrent Suite 3.0 is supposed to have dramatic improvements in base-calling. Ion Torrent on Twitter quote Shawn Levy at Hudson Alpha saying: “Concerns about insertion deletion errors are now largely solved”. Chad Nusbaum is quoted as saying: “Indel mismatches significantly improved in the new bioinformatics software Torrent suite 3.0″. This is great news. Certainly the recent E. coli 300bp dataset put out on the Ion Torrent website look a great deal better than that which we got in summer 2011. [...]
[...] [2] http://pathogenomics.bham.ac.uk/blog/2012/05/benchtop-sequencer-comparison-paper/ [...]