High-throughput sequencing

The biggest genome sequencing projects: the uber-list!

I am just writing a short presentation for a meeting in Hinxton. I wanted to demonstrate the profound effect that whole-genome sequencing is having on the study of biology, and the size and scope of recent studies. So I thought it would be fun to catalogue the largest – in terms of samples – genome […]

Sequencing data: I want the truth! (You can’t handle the truth!)

Sequencing data: I want the truth! (You can’t handle the truth!)

Two sequencing papers caught my eye this week. This letter from Piskol and Li  is perhaps the final nail in the coffin for the heavily criticised and debunked (also see: GenomesUnzipped) RNA editing paper from Li and Cheung published in Science in early 2011 (as Thomas Keane said on Twitter: ‘I can’t believe people are still debating this!). The letter Piskol and Li examined […]

COST training school: Bioinformatics for microbial community analysis

I will be helping teach one day of this course which is fully-funded if you are a student from a COST-participating country… see below for details: Deadline is next week, so hurry if you are interested. COST training school ES1103: Bioinformatics for microbial community analysis Dates: December 11th- 14th (the school will begin at 1pm […]

Properly awesome: HiSeq 2500 2×151 rapid run streaming to BaseSpace

Properly awesome: HiSeq 2500 2×151 rapid run streaming to BaseSpace

OK, I think this is awesome enough to share with you guys. These are some metagenomics samples being run on a HiSeq 2500 in 2x151bp rapid run mode, with the results being streamed to BaseSpace in real-time. What I love about this is that the various statistics and metrics update in real-time. I spent a […]

Some thoughts on today’s Ion World announcements

Some thoughts on today’s Ion World announcements

A few significant announcements from Ion World today (sourced from the press release and #ionworld Tweets) which I’ve summarised here: Proton III and Avalanche The Ion Proton is now shipping and Life Tech plan to ship 100 instruments to customers in September. The initial chip, Proton I (“PI”) will do 60-80m reads and “up to 10Gb” of […]